Öz
Amaç
Obezite hipoventilasyon sendromu (OHS), obeziteye ek olarak solunum fonksiyon bozukluğu ile karakterizedir ve egzersiz kapasitesini, periferik kas gücünü ve yaşam kalitesini olumsuz yönde etkileyebilir. Bu çalışmanın amacı, obez bireylerde OHS’nin egzersiz kapasitesi, periferik kas gücü ve yaşam kalitesi üzerindeki etkilerini araştırmaktır.
Yöntemler
Çalışmaya 32’si OHS’li ve 32’si basit obez olmak üzere toplam 64 katılımcı dahil edilmiştir. Demografik ve klinik veriler kaydedilmiştir. Klinik verileri içerisine polisomnografi sonuçları ile komorbid durumları (Charlson komorbidite indeksi) kaydedilmiştir. Egzersiz kapasitesi altı dakika yürüme testi ile değerlendirilmiş, periferik kas gücü dijital el dinamometresi ve hidrolik el dinamometresi kullanılarak ölçülmüştür. Yaşam kalitesi Nottingham sağlık profili (NHP) ile uyku kalitesi ise Pittsburgh Uyku kalitesi indeksi (PSQI) ile değerlendirilmiştir. Vücut kompozisyonu ve çevresel ölçümler kaydedilmiştir.
Bulgular
Basit obez grubunun altı dakika yürüme mesafesi [500,44±40,46; p=0,021; %95 güven aralığı (GA)=0,59] ve sağ ve sol kuadriseps kas güçleri (186,66±35,14; p=0,004; %95 CI=0,75) (184,56±34,56; p=0,005; %95 GA=0,74) anlamlı olarak daha yüksekti. OHS grubunun NHP toplam (243,13±105,54; p<0,001; %95 GA=1,75) ve alt skorları [enerji düzeyi (58,90±35,51; p=0,001; %95 GA=0,87), duygusal durum (31,81±29,73; p=0,029; %95 GA=0,56), uyku (43,60±26,01; p<0,001; %95 GA=1,96), PSQI toplam skoru (8,66±3,98; p=0,001; %95 GA=2,14) ve boyun çevresi (42,62±3,77; p=0,025; %95 GA=0,57) anlamlı derecede yüksek bulundu. Diğer sonuç ölçütlerinde istatistiksel olarak anlamlı bir fark elde edilmedi (p>0,005).
Sonuç
Bu bulgular, OHS’li bireylerin basit obez bireylere kıyasla daha düşük egzersiz kapasitesine ve kas gücüne sahip olduğunu, ayrıca yaşam ve uyku kalitelerinin daha kötü olduğunu göstermektedir. Bu durum, OHS hastalarında fiziksel fonksiyon ve genel iyilik halini iyileştirmeye yönelik hedefe yönelik müdahalelerin gerekliliğini vurgulamaktadır.
Anahtar Kelimeler: Obezite hipoventilasyon sendromu, obezite, egzersiz kapasitesi, periferik kas gücü, yaşam kalitesi
Kaynakça
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