Öz
Labial füzyon (LF) çoğunlukla asemptomatiktir ve herhangi bir klinik şikayete yol açmamaktadır. LF patofizyolojisinde “hipoöstrojenemi”nin önemli rol oynadığı düşünülmüştür. Hipoöstrojenize ortamda sık ve aşındırırcasına yapılan perine temizliği lokal inflamasyon, epitelin deskuamasyonu ve doku iyileşmesi sırasında füzyonla sonuçlanmaktadır. Asemptomatik olan hastalarda herhangi bir müdahale gerekmemekle beraber aileyi telarş zamanı geldiğinde kanda östrojen miktarının yükselmesiyle beraber LF’nun kendiliğinden çözüleceği konusunda rahatlatmak yeterlidir. Ancak enflamasyon bulguları, vajinit, idrar yolu enfeksiyonu gelişirse geleneksel olarak kullanılan ilk tedavi yaklaşımı krem şeklinde topikal düşük doz östrojen tedavisidir. Topikal betametazon tedavisi de etkin bir alternatiftir. Medikal tedavi ile LF gerilemezse veya tekrar eden uygulamalarda rekürrens gelişirse labiumların manuel seperasyonu veya keskin insizyonla cerrahi ayrıştırılması gerekebilir. Tedavide hangi yöntem kullanılırsa kullanılsın aileye rekürrens olasılığı hakkında bilgi verilmelidir. Rekürrens riski artan yaşla ve endojen östrojen üretiminin artmasıyla azalır. Rekürrense katkıda bulunan faktörler arasında kötü genital hijyen, tekrarlayan vulvovajinitler ve vulvar dermatozlar yer almaktadır.
Anahtar Kelimeler: Labial füzyon, labial adezyon, labial sineşi, labial aglütinasyon
Kaynakça
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