ÖZET

Amaç:

Elektrokonvülzif terapi (EKT) depresyon ve psikozun akut tedavisinde uzun süredir kullanılan bir nöromodülasyon tedavisidir. Bununla birlikte, hastaların iyilik hallerinin devam etmesi için farmakoterapiye oranla uygulaması daha az bilinen ve tercih edilen bir sürdürüm tedavi şeklidir. Son yıllarda, akut alevlenme tedavisi sonrası sürdürüm tedavisinde de yineleyici depresif bozuklukta ve tedaviye dirençli şizofrenide kullanılmaya başlanmıştır.

Yöntem:

Bu çalışmada 2015-2018 yılları arasında yineleyici depresif bozukluk (10) ve tedaviye dirençli şizofreni (14) tanısı ile idame EKT tedavisi alan 24 hastanın verileri retrospektif olarak incelenmiştir.

Bulgular:

Remisyon oranları her iki grupta %70 olarak tespit edilmiştir. Hiçbir hasta EKT’ye bağlı yan etkiler nedeniyle tedaviyi bırakmamıştır.

Sonuç:

EKT tedavisi hakkındaki ön yargılar ve hastaların damgalanma yaşaması özellikle ayaktan hastalar için az tercih edilen bir tedavi olmasına neden olmaktadır. Ancak literatür verileri incelendiğinde EKT’nin morbidite ve mortalitesinin oldukça düşük olduğu görülmektedir. Bizim bulgularımız retrospektif bir analiz sonucu elde edilmiş olsa da idame EKT’nin yineleyici depresif bozukluk ve tedaviye dirençli şizofreninin sürdürüm tedavisi için bir seçenek olabileceğini göstermektedir. Ancak bulguların gelecek randomize kontrollü çalışmalarla da desteklenmesi gerekmektedir.

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Yineleyici Depresif Bozukluk ve Tedaviye Dirençli Şizofrenide İdame EKT

ÖZET

References