ÖZET
Amaç:
Bu çalışmanın amacı, idiyopatik ani sensörinöral işitme kaybı (İASİK) olan hastaların serum melatonin düzeylerini ortaya koymaktır.
Yöntemler:
İASİK olan 22 hasta ve 22 asemptomatik sağlıklı gönüllü çalışmaya dahil edildi. Katılımcılara saf ses odyometrisi uygulandı ve katılımcıların serum melatonin seviyeleri ölçüldü.
Bulgular:
Hasta grubunda 12 kadın [ortalama (ort.) yaş: 46,41±7,8] ve 10 erkek (ort. yaş: 48±6,46) vardı. Kontrol grubunda 12 kadın (ort. yaş: 40,25±5,28) ve 10 erkek (ort. yaş: 38,4±27,08) vardı. Serum melatonin düzeylerinin hasta grubunda kontrol grubuna göre anlamlı derecede düşük olduğu saptandı (p≤0,001). Serum melatonin seviyesi ile işitme kaybının şiddeti arasında istatistiksel olarak anlamlı güçlü negatif bir korelasyon vardı (r=-0,644; p=0,001).
Sonuç:
İASİK olan hastaların serum melatonin düzeyleri kontrol grubundan daha düşüktü. Serum melatonin seviyesi ile işitme kaybının şiddeti arasında istatistiksel olarak anlamlı güçlü negatif bir korelasyon vardı.
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