Sezaryen için Optimal Anestezi Tekniğinin Değerlendirilmesi, Anne ve Yenidoğan Üzerine Etkileri
PDF
Atıf
Paylaş
Talep
P: 411-417
Ekim 2020

Sezaryen için Optimal Anestezi Tekniğinin Değerlendirilmesi, Anne ve Yenidoğan Üzerine Etkileri

Bezmialem Science 2020;8(4):411-417
Bilgi mevcut değil.
Bilgi mevcut değil
Alındığı Tarih: 17.12.2019
Kabul Tarihi: 13.09.2019
Yayın Tarihi: 30.10.2020
PDF
Atıf
Paylaş
Talep

ÖZET

Amaç:

Sezaryen ile doğumlarda rejyonal anestezi çoğunlukla tercih edilir. Bu çalışmada genel, epidural ve spinal anestezi tekniklerinin fetal ve maternal etkileri açısından karşılaştırılması amaçlandı

Yöntemler:

Sezaryen ile doğum yapan gebeler rastgele üç gruba ayrıldı: genel anestezi (GA), epidural anestezi (EA) ve spinal anestezi (SA). APGAR skoru, fetal kan gazı seviyesi, serbest O2 gereksinimi ve pozitif basınçlı ventilasyon, fototerapi gereksinimi, bilirubin seviyesi ve kilo kaybı kaydedildi. Ayrıca ilk emzirme zamanı, perioperatif kanama, kristalloid gereksinimi, efedrin tüketimi, ilk analjezik gereksinimi, ilk defekasyon ve mobilizasyon süresi ölçüldü.

Bulgular:

APGAR skorları ve SpO2 GA grubunda düşüktü (p<0,05). Altı yenidoğanda O2 desteği ve pozitif basınçlı ventilasyon gerekti ve GA grubundan bir yenidoğan entübe edildi ve NICU'ya transfer edildi. İlk emzirme zamanı GA grubunda diğer gruplara göre uzadı (p<0,05). Yenidoğanların doğum sonrası 48 saatlik kilo kaybı EA ve SA gruplarında GA grubundan daha yüksekti (p <0,05). Peropertif kanama GA grubunda daha yüksekti. SA grubunda, efedrin ve sıvı gereksinimleri daha yüksekti ve mobilizasyon süresi daha kısa idi (p<0,05). İlk analjezik gereksinimi ve ilk defekasyon süresi EA grubunda daha kısaydı (p<0,05).

Sonuç:

Genel anestezi ile, daha düşük APGAR skorları, serbest O gereksinimi ve daha sık pozitif basınçlı ventilasyon gereksinimi ve ilk emzirme zamanı rejyonel anestezi ile karşılaştırıldığında daha uzundu. Bu nedenle sezaryen ile doğumda rejyonel teknikler tercih edilebilir.

References

1
Lesage S. Cesarean delivery under general anesthesia: continuing professional development. Can J Anaesth 2014;61:489–503.
2
Yamashita A, Irikoma S. Comparison of inflationary non-invasive blood pressure (iNIBP) monitoring technology and conventional deflationary non-invasive blood pressure (dNIBP) measurement in detecting hypotension during cesarean section. JA Clin Rep 2018;4:5.
3
Malin GL, Morris RK, Khan KS. Strength of association between umbilical cord pH and perinatal and long term outcomes: systematic review and meta-analysis. BMJ 2010;340:c1471.
4
Jain K, Makkar JK, Subramani Vp S, Gander S, Kumar P. A randomized trial comparing prophylactic phenylephrine and ephedrine infusion during spinal anesthesia for emergency cesarean delivery in cases of acute fetal compromise. J Clin Anesth 2016;34:208–15.
5
Mardirosoff C, Dumont L, Boulvain M, Tramer MR. Fetal bradycardia due to intrathecal opioids for labour analgesia: a systematic review. BJOG 2002;109:274–81.
6
Hattler J, Klimek M, Rossaint R, Heesen M. The effect of combined spinal-epidural versus epidural analgesia in laboring women on nonreassuring fetal heart rate tracings: systematic review and meta-analysis. Anesth Analg 2016;123:955–64.
7
Hess PE. What’s new in clinical obstetric anesthesia in 2015? Int J Obstet Anesth 2017;32:54–63.
8
Strouch ZY, Dakik CG, White WD, Habib AS. Anesthetic technique for cesarean delivery and neonatal acid-base status: a retrospective database analysis. Int J Obstet Anesth 2015;24:22–9.
9
Ikonomidou C, Bosch F, Miksa M, Bittigau P, Vockler J, Dikranian K, et al. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 1999;283:70–4.
10
Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, et al. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci 2003;23:876–82.
11
Popic J, Pesic V, Milanovic D, Loncarevic-Vasiljkovic N, Smiljanic K, Kanazir S, et al. Induction of TNF-alpha signaling cascade in neonatal rat brain during propofol anesthesia. Int J Dev Neurosci 2015;44:22–32.
12
Clark RB. Hypotension and caesarean section. Br J Anaesth 2008;101:882–3.
13
Afolabi BB, Lesi FEA. Regional versus general anaesthesia for caesarean section. Cochrane Database Syst Rev 2012;10:CD004350.
14
Nishikawa K, Yokoyama N, Saito S, Goto F. Comparison of effects of rapid colloid loading before and after spinal anesthesia on maternal hemodynamics and neonatal outcomes in cesarean section. J Clin Monit Comput 2007;21:125–9.
15
Morgan PJ, Halpern SH, Tarshis J. The effects of an increase of central blood volume before spinal anesthesia for cesarean delivery: a qualitative systematic review. Anesth Analg 2001;92:997–1005.
16
Lertakyamanee J, Chinachoti T, Tritrakarn T, Muangkasem J, Somboonnanonda A, Kolatat T. Comparison of general and regional anesthesia for cesarean section: success rate, blood loss and satisfaction from a randomized trial. J Med Assoc Thai 1999;82:672–80.
17
Aly HA, Ramadani HM. Assessment of blood loss during cesarean section under general anesthesia and epidural analgesia using different methods. AJAIC 2006;9:25–34.
18
Kamat SK, Shah MV, Chaudhary LS, Pandya S, Bhatt MM. Effect of induction-delivery and uterine-delivery on apgar scoring of the newborn. J Postgrad Med 1991;37:125–7.
19
Steinbrook RA. Epidural anesthesia and gastrointestinal motility. Anesth Analg 1998;86:837–44.
20
Fotiadis RJ, Badvie S, Weston MD, Allen-Mersh TG. Epidural analgesia in gastrointestinal surgery. Br J Surg 2004;91:828–41.
21
Solangi SA, Siddiqui SM, Khaskheli MS, Siddiqui MA. Comparison of the effect of general and spinal anesthesia on neonatal outcome. Anaesth Pain Intensive Care 2012;16:18–23.
22
Kavak ZN, Basgul A, Ceyhan N. Short-term outcome of newborn infants: spinal versus general anesthesia for elective cesarean section. A prospective randomized study. Eur J Obstet Gynecol Reprod Biol 2001;100:50–4.
23
Petropoulos G, Siristatidis C, Salamalekis E, Creatsas G. Spinal and epidural versus general anesthesia for elective cesarean section at term: effect on the acid-base status of the mother and newborn. J Matern Fetal Neonatal Med 2003;13:260–6.
24
Yeğin A, Ertuğ Z, Yılmaz M, Erman M. The effects of epidural anesthesia and general anesthesia on newborns at cesarean section. Türk J Med Sci 2003;33:311–4.
25
Wiklund I, Norman M, Uvnas-Moberg K, Ransjo-Arvidson AB, Andolf E. Epidural analgesia: breast-feeding success and related factors. Midwifery 2009;25:e31–8.
26
Wilson MJ, MacArthur C, Cooper GM, Bick D, Moore PA, Shennan A. Epidural analgesia and breastfeeding: a randomised controlled trial of epidural techniques with and without fentanyl and a non-epidural comparison group. Anaesthesia 2010;65:145–53.
27
Szabo AL. Intrapartum neuraxial analgesia and breastfeeding outcomes: limitations of current knowledge. Anesth Analg 2013;116:399–405.
28
WHO. Pregnancy, childbirth, postpartum and newborn care: a guide for essential practice. 3rd ed. Geneva, Switzerland. 2015. Available from: URL: https://apps.who.int/iris/bitstream/handle/10665/249580/9789241549356-eng.pdf; jsessionid=4C00762DE3 DA9B38B4 69DF10 50F2FEB3?sequence=1
29
Tonni G, Ferrari B, De Felice C, Ventura A. Fetal acid-base and neonatal status after general and neuraxial anesthesia for elective cesarean section. Int J Gynaecol Obstet 2007;97:143–6.
30
Ozcakir HT, Lacin S, Baytur YB, Luleci N, Inceboz US. Different anesthesiologic strategies have no effect on neonatal jaundice. Arch Gynecol Obstet 2004;270:179–81.
31
Demiraran Y, Albayrak M, Seker IS, Kaynak G, Iskender A, Sezen GY, et al. Effect of anesthesiological strategies on neonatal bilirubin levels during cesarean section: a prospective and randomized trial. Arch Gynecol Obstet 2011;284:1059–65.
2024 ©️ Galenos Publishing House