Introduction

In December 2019, a new type of coronavirus, which is rapidly transmitted from person to person and has a high mortality, emerged in Wuhan, China. Today, there is no special antiviral treatment and vaccine to protect against the new type of Coronavirus disease-19  (COVID-19). This situation negatively affected the health systems of all countries in the world (1-5); the high numbers of patients experienced in hospitals caused disruption or postponement of outpatient, diagnostic and surgical procedures. At the same time, the new type of coronavirus pandemic process has led to changes and improvements in the health systems of countries (6). During the pandemic period, especially since the lack of some innovations in the health system, new and creative approaches were needed and it was revealed that innovation was critical in the health system (7-9). Therefore, countries have tried to face the pandemic by developing their digital infrastructure and engineering capabilities. In addition, the spread of COVID-19 has been tried to be mitigated by developing action plans with technologies that provide community-driven and communication tracking and by implementing some practices (10,11). In this review, we aimed to address the innovation made in the health care systems in the world and in Turkey during the new type of coronavirus pandemic period.

New Type of Coronavirus (COVID-19)

Coronaviruses are single-stranded RNA viruses that mostly infect birds and mammals and belong to the coronaviridae family. These viruses have been seen in humans as SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) disease (1,12,13). Today, a new coronavirus has been found that infects humans. The virus is expressed with the word “corona”, which means crown in Latin, and named temporarily “2019-nCoV” and updated to COVID-19 as of February 12, 2020 (2,3). This virus can be transmitted rapidly from person to person through droplets and contact (1,14). Coronavirus causes symptoms such as fever, cough, dyspnea, fatigue, nausea, vomiting and diarrhea in humans. In severe cases, dyspnea, severe acute respiratory tract infection, kidney failure and pneumonia are seen. Death may occur depending on the progression of the disease (1,4).

Effect of COVID-19 on Health System

COVID-19 spread among people in a short period of time and affected the whole world and was classified as a pandemic by the World Health Organization (WHO). Until now, the total number of cases in the world has been reported as 8,349,972 and the total number of deaths as 448,962 (15). This indicates that the virus is rapidly transmitted and its mortality is high. Although there is no vaccine and specific treatment developed so far to prevent COVID-19, studies continue in many countries (1,4,5,16). The increase in patient numbers in hospitals due to COVID-19 has led to the disruption of the outpatient clinic services and other services provided to the patients and the delay of the surgeries (16). Countries have implemented emergency action plans by developing various strategies in order to solve the problems experienced in their health systems, to isolate suspicious cases and to prevent the spread of the disease (5,16). The precautions included in these action plans and these required to be implemented are non-pharmacological public health measures such as isolation, social distance and quarantine. Isolation includes segregation of symptomatic patients, and quarantine includes restriction of asymptomatic healthy individuals who have come into contact with confirmed or suspected cases. Quarantine can be applied on a voluntary basis or legally by the authorities at the individual, group or community level. These methods are known as the most effective way to respond to the pandemic (14,17). In addition, countries have followed the guidelines and recommendations put forward by global institutions (such as CDC, WHO) in health systems. Strict implementation of these measures is essential to reduce the spread of disease and prevent health system collapse. However, as there are serious gaps in developed economies and health systems, new and creative approaches in health services were required to learn, experience and able to connect during the pandemic (7,8,14). These new and creative approaches are listed below.

Telemedicine Applications

Telemedicine applications, which have a recent history in health care systems, started to be used more in the COVID-19 pandemic period. These web-based applications, in which electronic patient records are used to reduce the number of individuals applying for health services, are called “telemedicine”. Telemedicine is a system that allows physicians and patients to communicate 24/7 using smart phones or computers and includes classification before they come to the emergency room. In addition, telemedicine is a system that was made available to all primary care patients in the healthcare system during the COVID-19 pandemic, and patients are guided according to whether they have symptoms of COVID-19. If the individual is asymptomatic, the presence of contact history with any known case is questioned and information is given about COVID-19 disease.  If the individual is symptomatic, patients are divided into four categories (requiring urgent intervention, urgent, non-urgent or self-sufficient) and connected to the COVID-19 unit via telephone after planning. Respiratory symptoms that may be early signs of COVID-19, travel and contact histories of patients are among the most frequently evaluated conditions with this approach. Thus, the density in hospitals can be prevented, and the exposure of healthcare workers to COVID-19 is reduced. Another example of telemedicine applications is the “JeffConnect®” application. Patients can access this system with their user names and passwords via their mobile phone or computer system. In the system, the patient first fills in his personal information (location, phone number, nearest pharmacy, height, weight, etc.), and then information about his current illness (symptoms such as allergies, cough, constipation, diarrhea, etc.). Depending on the patient’s complaint, the physician prescribes medication or gives information about the disease. With this system, physicians and healthcare professionals can provide consultancy services to patients who experience COVID-19 symptoms at any time via a mobile phone/tablet or a computer with a webcam. In addition, with this system, when patients with suspected COVID-19 need to be tested, central coordination can be achieved with healthcare personnel as well as local test institutions (18-21).

For telemedicine applications in our country, “ALO 184 Corona Information Line” (SABİM)  has started to serve. With this application, individuals are guided by obtaining information from specialist physicians in case of COVID-19 symptoms (22). All of these applications have been developed to prevent unnecessary hospital applications during the pandemic by making the triage system more effective. These methods are patient-centered, convenient for individuals to self-quarantine and reduce the virus burden of healthcare workers.

Mobile Applications

Another technology developed during the COVID-19 pandemic is mobile applications. “TraceTogether” and “Coronavirus Pandemic Epidemiology (COPE)” are some of these applications. With these mobile applications, it provides many data such as demographic and clinical information of individuals, symptoms, test results, quarantine tracking of infected individuals and accessing the contact history of an infected individual and a healthy individual. In addition, applications provide guidelines for individuals regarding coronavirus disease, transmission routes, online screening tool, testing or situations requiring emergency intervention (23-27).

In Turkey, with the scope of COVID-19 combat, the Ministry of Health developed a mobile application named “Hayat Eve Sığar-HES”, in which citizens can follow the risks and health conditions.  In the HES application, individuals fill out the questionnaire regarding their own health status and can easily access the latest developments regarding the virus, the risk map of their location, the closest health institution, pharmacy, market chain, metro and stations. This practice aims to minimize the risks associated with the epidemic that may be experienced and to prevent its spread (28).

Another application developed by the Ministry of Health is the “Korona Önlem” application. With this application, the risk status of the individual is calculated as a result of inquiries about identity information, personal information, chronic diseases, travel history and complaints, and guidance is made (29).

Web-based Applications

Web-based maps were created to facilitate the tracking of the virus during the COVID-19 pandemic period. The map “Coronaviz.umiacs.io” is one of the web based maps. This application was developed in order to predict the emergence of the virus in new regions and to make countries more ready for the epidemic process (30). In this way, the regional spread of the virus can be seen in the world. In China, Lian Fei Technology has established a blockchain platform, providing up-to-date case numbers in the COVID-19 pandemic, ensuring the clarity of information, transparency and traceability of developments (31,32). In addition, the Global MediXchange platform, developed by the Alibaba cloud and Jack Ma Foundation, made available the studies on the subject using information and artificial intelligence technology and shared them with healthcare professionals around the world. In this way, online communication and cooperation between countries has been facilitated and experiences experienced during the pandemic process are shared with other countries in the world (33).

In our country, there are web-based applications within the scope of coronavirus studies. TUBITAK and Ministry of Industry and Technology together, in cooperation, implemented “COVID-19 Turkey Web Portal” and COVID-19 Pandemic Follow-up Display (TURCOVID19)”, applications, which are among these web-based applications. In COVID-19 Turkey Web Portal, COVID-19 cases of instant availability and data are shared taht were gained by researchers engaged in research on the subject in Turkey and in the World, whereas in Turkey COVID-19 Pandemic Follow-Up Display (TURCOVID19) application, information about the cases of death and improving patient numbers, applied to the number of tests, the data in the case-fatality rate (VÖO), intensive care admission and intubated patient categories are shared with the public daily and visually (34,35).

Psychological Support Practices

Countries that anticipate that psychological side effects (fear, panic in the society) that develop due to isolation during the pandemic process may cause more harm than COVID-19 have attached importance to protecting the mental health of the society. Therefore, applications such as text messaging, chat, telephone, video conferencing, websites, mobile applications, online self-help platform and online group chat have been developed (36). With these practices, it was aimed to support societies by enabling individuals to cope more easily with feelings of fear, panic and helplessness in the face of uncertainty (37). In our country, “Corona Psychosocial Support Line” and “Corona Information and Counseling Line” have been put into practice to provide psychological counseling (38).

Other Developed Applications

In addition to the applications mentioned above, different applications have also come up. Home evaluation teams, virtual maintenance centers and 3D printers that produce equipment are some of them. The home evaluation team has been set up to provide real-time clinical assessments of patients who do not require emergency medical care or hospitalization. This model facilitated access to the COVID-19 test for patients, reducing complexity, and benefiting the health system by increasing safety and efficiency (39). In order to conduct a similar filiation/field examination in our country, an expert team has been formed to screen the relatives/contacts of positive cases. The filiation / field investigation team aimed to work on the determination of the source and the agent and to increase protection and control measures, including those who had contact with the virus (40). Another application is virtual care centers. This application includes an electronic intensive care unit monitoring program that allows nurses and physicians to remotely monitor the status of 60 to 100 patients hospitalized in the intensive care units of more than one hospital. This practice is an application that reduces the contact of healthcare professionals with infected patients in the intensive care unit (7). Another application is 3D printers that produce equipment. During the pandemic process, an innovative technology, three-dimensional (3D) printer, was used to ensure adequate production and distribution of medical products due to the limited number of N95 respirators, face shields, ventilator valves, test kits and other individual protective equipment (41,42). This new technology has enabled healthcare workers at the forefront of my pandemic to be provided with adequate equipment and vital products for patients.

As a result, it is seen that technology is used effectively in the COVID-19 pandemic process. Telemedicine, mobile and web applications are among the applications that enter our lives actively in this process. The use of technology has provided benefits in many aspects such as reducing the number of admissions in emergency services and the virus load of healthcare personnel, monitoring patients at home, protecting the mental health of the community, producing sufficient equipment and facilitating access to academic studies. It is thought that the innovations brought by technology to our lives during and after the COVID-19 process will be permanent. However, it is thought that these practices may have deficiencies such as the inability of health professionals to perform physical examinations, being based on the patient’s statement, not necessarily using the applications, having difficulties in accessing technological infrastructure, and individuals not being able to use technology. Therefore, it is recommended to conduct studies evaluating the positive and negative aspects of these applications, and their effectiveness on patients and healthcare professionals.

Peer-review: Externally peer reviewed.

Authorship Contributions

Concept: Y.G., E.K.G., D.Ç., Design: Y.G., E.K.G., D.Ç., Data Collection or Processing: Y.G., E.K.G., D.Ç., Analysis or Interpretation: Y.G., E.K.G., D.Ç., Literature Search: Y.G., E.K.G., D.Ç., Writing: Y.G., E.K.G., D.Ç.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: This work was supported by Gilead Sciences.